Season 21(2008)
season - first aired/released 2008-09-01
Talk
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Cast
Regis PhilbinSelf - Host
Kelly RipaSelf - Host- Kristy Lee CookSelf
Ali LarterSelf
Richard GereSelf - Guest
Howie MandelSelf
America FerreraSelf - Guest
Keira KnightleySelf - Guest
Natasha BedingfieldSelf - Guest
Kate WalshSelf
Kellie PicklerSelf
Kevin ConnollySelf - Guest
Diane LaneSelf - Guest- LaDainian TomlinsonSelf - Guest
Blair UnderwoodSelf
Heidi MontagSelf - Guest
David Blaine- Jo FrostSelf - Guest
Show all 55 cast members
Leona LewisSelf - Guest
Benjamin BrattSelf - Guest
Julia Louis-DreyfusSelf - Guest
Christopher MeloniSelf - Guest
Meg Ryan- Alonzo Mourning
Wayne Brady
Robin ThickeSelf
Chace Crawford
Kevin Dillon
Samuel L. Jackson
Michael ChiklisSelf
Eva Mendes
Lori Loughlin
LeAnn RimesSelf
Jeremy PivenSelf - Guest
Jeff ProbstSelf - Guest
Shirley MacLaine
Phil McGrawSelf
Poppy MontgomerySelf - Guest
Jerry O'ConnellSelf
Dana DelanySelf
Calista Flockhart
Usain BoltSelf
Leighton MeesterSelf - Guest
Chris RockSelf - Guest
David BoreanazSelf - Guest
Vanessa WilliamsSelf - Guest
Brooke ShieldsSelf - Guest
Victoria BeckhamSelf - Guest
Nick LacheySelf - Guest
Ricky GervaisSelf- Jason ColthorpSelf - Host
Jimmy KimmelSelf - Guest Host
Spencer PrattSelf - Guest- Chris ByrneSelf - Guest
Kyle BuschSelf
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